Recombinant Human GDF3
GDF-3 is a growth and differentiation factor which belongs to the TGF-beta superfamily. GDF-3 and GDF-9 are the only two members of the family which do not form disulfide-linked dimers. GDF-3 has been found in adult bone marrow, spleen, thymus, and adipose tissue. Although signaling in all other members of the family involve the BMP receptors ALK1,2,3, and 6, GDF-3 signals through BMP receptors ALK4 and 7.
Product Specifications
CAS Number
9000-83-3
Gene Name
GDF3
Gene Aliases
GDF-3<br/>Recombinant Human Growth Differentiation Factor 3 (GDF3)
Gene ID
9573
Accession Number
Q9NR23
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 0.1mg/mL in 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Function
Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells.
Molecular Weight
13
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from solution in 30mM Acetate buffer, pH 4
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