Recombinant Human FGF6

FGF-6 is a heparin binding protein of the FGF family which works to control cell division, differentiation, and function. These proteins are especially prominent during prenatal development and postnatal growth. It has been shown that FGF-6 functions as a mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells (N-linked glycosylation is required for the full mitogenic effect). It has also been shown that FGF-6 inhibits the terminal differentiation of myoblasts, cooperates with TGF-2-beta to promote chondrogenesis in embryonic somites, and is present in leukemia cell lines which may undergo platelet megakaryocytic differentiation.