Recombinant Human Eotaxin (CCL11)
Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.
Product Specifications
CAS Number
9000-83-3
Gene Name
CCL11
Gene Aliases
SCYA11, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11
Gene ID
6356
Accession Number
P51671
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Activity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100 ng/mL.
Molecular Weight
8.5
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from as 0.2 μm filtered solution in PBS (pH 7.5)
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