Recombinant Human ENA-78 (CXCL5)
Epithelial neutrophil- activating protein 78 (ENA-78) is a member of the CXC chemokines and acts as a potent chemoattractant and activator of neutrophil function. On stimulation in vitro, ENA-78 is highly expressed in many cell types. ENA-78 protein levels are strongly elevated in synovial fluid and blood of patients with rheumatoid arthritis. By in situ hybridization and immunofluorescence staining, ENA-78 has been recognized as a major CXC chemokine expressed in epithelial cells of the intestinal mucosa of patients with Crohn's disease, ulcerative colitis, and acute appendicitis.
Product Specifications
CAS Number
9000-83-3
Gene Name
CXCL5
Gene Aliases
Accession Number
P42830
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Determined by its ability to chemoattract human neutrophils using a concentration range of 2.0 - 40.0 ng/mL.
Molecular Weight
8
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 µm filtered solution in 20 mM PB, 100 mM NaCl solution pH 7.5.
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