Recombinant Human EG-VEGF (PROK1)
This factor is identical to prokineticin-1 and is a member of the AVIT protein family. Expression of human EG-VEGF messenger RNA is restricted to the steroidogenic glands, ovary, testis, adrenal and placenta and is often complementary to the expression of VEGF. EG-VEGF has been identified as a mitogen specific for the endothelium of steroidogenic glands. EG-VEGF resembles VEGF in that it causes extensive angiogenesis and cyst formation when delivered in the ovary. EG-VEGF differs from VEGF in that it does not promote angiogenesis in the cornea or skeletal muscle. Two receptors have been characterized and are expressed in gastrointestinal organs, endocrine glands and other tissues. The G-protein-coupled receptors ZAQ and I5E both function as the EG-VEGF receptor.
Product Specifications
CAS Number
9000-83-3
Gene Name
PROK1
Gene Aliases
EGVEGF, Mambakine, Prokineticin-1, PROK1<br/>Recombinant Human Endocrine Gland Vascular Endothelial Growth Factor (PROK1)
Gene ID
84432
Accession Number
P58294
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Not available.
Molecular Weight
10
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Recombinant EG-VEGF was lyophilized from a 0.2 μm filtered PBS solution.
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