Recombinant Human CTGF
Secreted by vascular endothelial cells, CTGF is a regulatory protein that has been shown to stimulate the growth of chondrocytes, promote angiogenesis and mediate cell adhesion of fibroblasts and endothelial cells. The binding of CTGF to heparin induces cell migration and adhesion. Mature Human CTGF is a 38.0 kDa secreted protein that is comprised of four distinct structural domains (a) IGFBP N-terminal domain (b) VWFC domain (c) TSP type-I domain and (d) C-terminal CTCK domain. Recombinant Human CTGF is an 11.3 kDa protein monomeric protein that maps to the CTCK domain.
Product Specifications
Gene Name
CTGF
Gene Aliases
Gene ID
1490
Accession Number
P29279
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Function
Determined by the dose-dependent stimulation of the proliferation of HUVEC cells. The expected ED50 for this effect is 1.0-2.0 µg/ml.
Molecular Weight
11.3
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2µm filtered solution containing 0.1% TFA
CAS Number
9000-83-3
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