What is the catalog number for Recombinant Human CCL22?

The catalog number for Recombinant Human CCL22 is Z101019.

What sizes are available for Recombinant Human CCL22?

Recombinant Human CCL22 is available in the following size(s): 1 mg.

Is Recombinant Human CCL22 in stock?

Recombinant Human CCL22 is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Human CCL22

CCL22 (monocyte-derived chemokine) was described initially as a constitutively produced, thymus-specific chemokine, implicated in the recruitment of T cells . One of the functions of CCL22 originally described was induction of migration of CCR4+ Th2 cells, but it has additionally been shown to regulate migration of Tregs. CCL22 has been implicated in a number of diseases, including allergen-induced lung inflammation, atopic dermatitis, and lymphoma. Similarly, a presumed role for CCR4+ cells has been suggested for endotoxic shock, rheumatoid arthritis, T cell lymphoma, and autoimmune diabetes

Product Specifications

CAS Number

9000-83-3

Gene Name

CCL22

Gene Aliases

STCP-1, ABCD-1, CCL22, CC chemokine STCP-1, MDC(1-69), SCYA22, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1, MDC, C-C motif chemokine 22 <br/>Recombinant Human Macrophage-Derived Chemokine (CCL22)

Gene ID

6367

Accession Number

O00626

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

The ED(50) was determined by the dose-dependent proliferation of MGC823 cells and was found to be <5ng/mL.

Molecular Weight

8

Shipping Conditions

Ambient Temperature

Storage Conditions

Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.