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Recombinant Human Beta-NGF

β-NGF is a potent neurotrophic factor that plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. β-NGF belongs to the cysteine-knot family of growth factors that assume stable, disulfide-linked homodimeric structures. Recombinant human β-NGF shares approximately 90% homology with both the mouse and rat βNGF at the primary level.

Product Specifications

CAS Number

9000-83-3

Gene Name

NGF

Gene Aliases

β-NGF, Nerve Growth Factor

Gene ID

4803

Accession Number

P01138

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

N.A.

Molecular Weight

14

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

Lyophilized from a 0.2µm filtered solution containing 0.1% TFA

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