Recombinant Human B-cell Maturation Protein (TNFRSF17)
BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes.The N-terminal part of both mouse and human proteins contains a conserved six-cysteine motif. BLyS binds to three receptors of the TNF receptor family (B cell maturation antigen BCMA, TACI, and BAFF-R), all of which are expressed by mature B cells.
Product Specifications
CAS Number
9000-83-3
Gene Name
TNFRSF17
Gene Aliases
Tumor necrosis factor receptor superfamily member 17, TNFRSF17, B cell maturation antigen, BCM, BCMA, CD269
Gene ID
608
Accession Number
Q02223
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method
Purity
>95% as determined by SDS-PAGE
Solubility
Function
The ED(50) was determined by the dose-dependent proliferation of KMS15 cells and was found to be <0.05ng/mL.
Molecular Weight
6
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS
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