Recombinant Human Activin A (INHBA)
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development and bone growth, depending on their subunit composition. Activin A is a disulfide linked homodimer (two beta-A chains) that binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin.
Product Specifications
CAS Number
9000-83-3
Gene Name
INHBA
Gene Aliases
Activin beta-A chain, Inhibin beta A chain, Erythroid differentiation protein, INHBA
Gene ID
3624
Accession Number
P08476
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Not required
Function
N.A.
Molecular Weight
13
Shipping Conditions
Dry Ice
Storage Conditions
Store at 4⁰C, if the product will be used within 4 weeks. Store at -20⁰C for longer periods of time.
Appearance
Liquid
Formulation
Activin A is supplied in 20mM Tris-HCl, 1mM EDTA and 50% Glycerol.
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