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Human IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker) (IG507R), CF640R conjugate, 0.1mg/mL

This antibody recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

G1m Marker; G2m Marker; G3m Marker; G4m Marker; HDC; Heavy Chain Disease Protein; Human Immunglobulin G; Ig gamma1/2/3/4 Chain C Region; IGHG1; IGHG2; IGHG3; IGHG4; Immunoglobulin Heavy Constant 1/2/3/4

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

IGHG

Gene ID

3500 (IGHG1)|3501 (IGHG2)|3502 (IGHG3)|3503 (IGHG4) (Human)

NCBI Gene ID

510635

UniProt

P01857|P01859|P01860|P01861

Swiss Prot

P01857|P01859|P01860|P01861

Host

Rabbit

Species Reactivity

Human

Reactivity

Human IgG Heavy Chain

Immunogen

Purified human Ig Gamma Chain

Target Antigen

Human IgG Heavy Chain

Clonality

Recombinant Monoclonal

Clone

IG507R

Type

Anti-Human Immunoglobulin|Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer, Immunology, Inflammation

Positive Control

293T, Raji or hPBL cells. Tonsil or Spleen

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

75 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Product Datasheet

https://cdn.gentaur.com/products/37/896236/datasheet/bnc400507-500.pdf

Product MSDS

https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf

Fragment

IgG, kappa

Species

Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

CAS Number

9007-83-4

Conjugate

CF640R

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