5,15-Diphenylporphyrin
Selected Variant
HY-W035137-01
Size: 5 mg
5,15-Diphenylporphyrin (5,15-DPP) is an inhibitor of the oncogenic transcription factor STAT3. 5,15-Diphenylporphyrin specifically binds to the SH2 domain of STAT3, blocking the pTyr-SH2 interaction, thereby inhibiting the dimerization, nuclear translocation and DNA binding activity of STAT3, and ultimately inhibiting the expression of cancer cell-related genes. 5,15-Diphenylporphyrin can be used in research fields related to the development of anticancer drugs[1][2].
Product Specifications
CAS Number
22112-89-6
Product Name Alternative
5,15-DPP
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-15-diphenylporphyrin.html
Purity
95.0
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C1(/C2=CC=CC=C2)=C3C=CC(/C=C4C=C/C(N/4)=C(C5=CC=CC=C5)/C(C=C/6)=NC6=C/C7=CC=C1N7)=N/3
Molecular Formula
C32H22N4
Molecular Weight
462.54
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Human Kappa Light Chain (B-Cell Marker) (rKLC264), Biotin conjugate, 0.1mg/mL
Granulocyte-Colony Stimulating Factor (G-CSF) (CSF3) (CSF3/900), CF640R conjugate, 0.1mg/mL
CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF740 conjugate, 0.1mg/mL
Adipophilin / Perilipin-2 (Marker of Obesity) (ADFP/1366), CF740 conjugate, 0.1mg/mL
