5,15-Diphenylporphyrin
Product Specifications
UNSPSC Description
5,15-Diphenylporphyrin (5,15-DPP) is a selective STAT3-SH2 antagonist (IC50s of 0.28 µM and 10 µM for STAT3 and STAT1, respectively)[1].
Target Antigen
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-15-diphenylporphyrin.html
Purity
95.0
Solubility
DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
C1(/C2=CC=CC=C2)=C3C=CC(/C=C4C=C/C(N/4)=C(C5=CC=CC=C5)/C(C=C/6)=NC6=C/C7=CC=C1N7)=N/3
Molecular Weight
462.54
References & Citations
[1]Uehara Y, et al. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009;380(3):627-631.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W035137/5-15-Diphenylporphyrin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W035137/5-15-Diphenylporphyrin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
22112-89-6
Available Sizes
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