Cdc7-IN-20
Product Specifications
UNSPSC Description
Cdc7-IN-20 (EP-05) is an orally effective and selective Cdc7 inhibitor with IC50 and Ki values of 0.93 and 0.11 nM, respectively. Cdc7-IN-20 has antitumor activity[1].
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc7-in-20.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(N)C(C)C)=NC2=C1SC(C3=CC=NC=C3)=C2
Molecular Weight
300.38
References & Citations
[1]Fu M, et al. Discovery of a potent and selective cell division cycle 7 inhibitor from 6-(3-fluoropyridin-4-yl) thieno [3, 2-d] pyrimidin-4 (3H)-one derivatives as an orally active antitumor agent. Acta Pharmaceutica Sinica. B, 2024, 14(2): 893.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163374/Cdc7-IN-20-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163374/
Clinical Information
No Development Reported
Curated Selection
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