Cdc7-IN-20

Cdc7-IN-20 (EP-05) is an orally effective and selective Cdc7 inhibitor with IC50 and Ki values of 0.93 and 0.11 nM, respectively. Cdc7-IN-20 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdc7-in-20.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(C(N)C(C)C)=NC2=C1SC(C3=CC=NC=C3)=C2

Molecular Formula

C15H16N4OS

Molecular Weight

300.38

References & Citations

[1]Fu M, et al. Discovery of a potent and selective cell division cycle 7 inhibitor from 6- (3-fluoropyridin-4-yl) thieno [3, 2-d] pyrimidin-4 (3H) -one derivatives as an orally active antitumor agent. Acta Pharmaceutica Sinica. B, 2024, 14 (2) : 893.