(R) -Vanzacaftor
(R) -Vanzacaftor ((R) -VX-121) is a regulator of cystic fibrosis transmembrane conduction regulator (CFTR) [1].
Product Specifications
CAS Number
2374124-48-6
Product Name Alternative
(R) -VX-121
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-vanzacaftor.html
Purity
98.07
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(C[C@](CCC/N=C1NC(S(=O)(N2)=O)=CC=C\1)([H])C3)N3C4=NC(N(C=C5)N=C5OCCC6C7(CC7)C68CC8)=CC=C4C2=O
Molecular Formula
C32H39N7O4S
Molecular Weight
617.76
References & Citations
[1]Jeremy J. Clemens, et al. Modulators of Cystic Fibrosis Transmembrane Conductance Regulator, Pharmaceutical Compositions, Methods of Treatment, and Process for Making the Modulators. US20190248809A1.2019-08-15.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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