(R) -Vanzacaftor

(R) -Vanzacaftor ((R) -VX-121) is a regulator of cystic fibrosis transmembrane conduction regulator (CFTR) [1].

Product Specifications

CAS Number

[2374124-48-6]

Product Name Alternative

(R) -VX-121

UNSPSC

12352005

Target

CFTR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-vanzacaftor.html

Purity

98.07

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(C[C@](CCC/N=C1NC(S(=O)(N2)=O)=CC=C\1)([H])C3)N3C4=NC(N(C=C5)N=C5OCCC6C7(CC7)C68CC8)=CC=C4C2=O

Molecular Formula

C32H39N7O4S

Molecular Weight

617.76

References & Citations

[1]Jeremy J. Clemens, et al. Modulators of Cystic Fibrosis Transmembrane Conductance Regulator, Pharmaceutical Compositions, Methods of Treatment, and Process for Making the Modulators. US20190248809A1.2019-08-15.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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