TS-002266
TS-002266 is a small molecule TUT4/7 inhibitor with anti-leukemic effects. TS-002266 is promising for research of cancers[1].
Product Specifications
CAS Number
[2702325-64-0]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ts-002266.html
Purity
98.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(C(OC[C@H]2CCCN2C3=C(C=C4C(C(C(O)=O)=CN(C4=C3)C5=CC=C(N=C5)N6CC(C6)N(C)C)=O)Cl)=NC=C1)Cl
Molecular Formula
C31H32Cl2N6O5
Molecular Weight
639.53
References & Citations
[1]Triboulet R, et al. Targeting the synthetic lethal relationship between FOCAD and TUT7 represents a potential therapeutic opportunity for TUT4/7 small molecule inhibitors in cancer. Mol Cancer Ther. 2024 Sep 5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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