Tubulin inhibitor 46
Selected Variant
HY-161747
Size: 1 Each
Tubulin inhibitor 46 (Compound 21) is a potent tubulin assembly inhibitor. Tubulin inhibitor 46 has antiproliferative activities, with GI50 values of 0.0095-33 μM for cancer and non-cancerous cells. Tubulin inhibitor 46 can be used for the reserch of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-46.html
Smiles
O=C1NC2=CC=C(C[C@@H]3NC([C@@H](O)C(C)C)=O)C=C2[C@@]1(C)C4=C(C5=NC(C(OCC6=CC=CC=C6)=O)=CO5)N=C(O4)[C@H](C(C)(C)C)NC3=O
Molecular Formula
C36H39N5O8
Molecular Weight
669.72
References & Citations
[1]Kalnins T, et al. Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide. J Med Chem. 2024 Jun 13;67 (11) :9227-9259.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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