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MRP1 / ABCC1 (Multidrug Resistance Related Protein 1) (MRP1/1344), CF405S conjugate, 0.1mg/mL

The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

ABC29; ABCC1; ATP binding cassette sub family C (CFTR/MRP) member 1; ATP-binding cassette sub-family C member 1; GSX; Leukotriene C (4) transporter; LTC4 transporter; Multidrug resistance-associated protein 1 (MRP1)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

ABCC1

Gene ID

4363

NCBI Gene ID

391464

UniProt

P33527

Swiss Prot

P33527

Host

Mouse

Species Reactivity

Human

Reactivity

ABCC1|MRP1

Immunogen

Recombinant human full-length ABCC1

Target Antigen

ABCC1 | MRP1

Clonality

Monoclonal

Clone

MRP1/1344

Type

Primary

Source

Animal

Origin

Animal

Field of Research

Cancer, Transporters

Positive Control

A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

190 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2a

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF405S

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