DiABZI STING agonist-1 (trihydrochloride)
DiABZI STING agonist-1 (trihydrochloride) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
Product Specifications
CAS Number
[2138299-34-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/diABZI_STING_agonist-1_Tautomerism_trihydrochloride.html
Purity
99.92
Solubility
DMSO : 90 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C5=C(OCCCN6CCOCC6)C=C(C(N)=O)C=C5N=C4NC(C7=CC(C)=NN7CC)=O.Cl.Cl.Cl
Molecular Formula
C42H54Cl3N13O7
Molecular Weight
959.32
Precautions
H302, H315, H319
References & Citations
[1]Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Available Sizes
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