USP7/USP47 inhibitor 1
USP7/USP47 inhibitor 1 (compound 2) is an inhibitor of USP47, with an EC50 of 14 μM. USP7/USP47 inhibitor 1 has an EC50 of >31.6 μM for USP7. USP7/USP47 inhibitor 1 can be used for cancer research[1].
Product Specifications
CAS Number
90680-28-7
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp7-usp47-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC([N+]([O-])=O)=C(SC2=CC=CC=C2)S1)=O
Molecular Formula
C12H9NO3S2
Molecular Weight
279.33
References & Citations
[1]Weinstock J, et al. Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47. ACS Med Chem Lett. 2012 Sep 11;3 (10) :789-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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