1-Methylguanosine

1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker[1].

Product Specifications

CAS Number

[2140-65-0]

Product Name Alternative

N1-Methylguanosine

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-Methylguanosine.html

Purity

99.57

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C)C(N)=N3)=O)O1

Molecular Formula

C11H15N5O5

Molecular Weight

297.27

Precautions

H315, H319, H335

References & Citations

[1]Liebich HM, et al. Quantitation of urinary nucleosides by high-performance liquid chromatography. J Chromatogr A. 1997 Feb 28;763 (1-2) :193-7.|[2]Jin X, et al., AtTrm5a catalyses 1-methylguanosine and 1-methylinosine formation on tRNAs and is important for vegetative and reproductive growth in Arabidopsis thaliana. Nucleic Acids Res. 2019 Jan 25;47 (2) :883-898.