Immunoproteasome inhibitor 1
Immunoproteasome inhibitor 1 is a potent, reversible, time-independent immunoproteasome and proteasome inhibitor (Kis of 1.18, 0.27, 1.91 μM in β5c, β1i, β5i submits, respectively) . Immunoproteasome inhibitor 1 can be used for the research of certain neoplastic diseases[1].
Product Specifications
CAS Number
[2755772-63-3]
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/immunoproteasome-inhibitor-1.html
Concentration
10mM
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C2=CC(OC)=C(OC)C=C2C=CN1C/C=C/C(NCCC(C)C)=O
Molecular Formula
C20H26N2O4
Molecular Weight
358.43
References & Citations
[1]Ettari R, et al. Development of isoquinolinone derivatives as immunoproteasome inhibitors. Bioorg Med Chem Lett. 2022;55:128478.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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