Nav1.8-IN-10
Nav1.8-IN-10 (Compound 6) is a Nav1.8 channel inhibitor. When the concentration is 4 nM, the percentage blocking rate of Nav1.8 channel is 79.4%. Nav1.8-IN-10 can be used in the study of pain disorders[1].
Product Specifications
CAS Number
[2664047-95-2]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-10.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(NC(C2=C(OC)C(C(F)(F)F)=NC=C2OC3=CC=C(C=C3OC)OC(F)(F)F)=O)C=CN1
Molecular Formula
C21H15F6N3O6
Molecular Weight
519.35
References & Citations
[1]Ao Li, et al. Selective sodium channel regulator and preparation and application thereof. CN113045487A. 2021-06-29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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