DMT-dC (bz) Phosphoramidite-13C9,15N3
DMT-dC (bz) Phosphoramidite-13C9,15N3 is the 13C and 15N labeled DMT-dC (bz) Phosphoramidite. DMT-dC (bz) Phosphoramidite is a deoxycytidine phosphoramide monomer with a protective group. DMT-dC (bz) Phosphoramidite is commonly used for synthesizing DNA dimers or trimers[1][2].
Product Specifications
CAS Number
2483830-14-2
UNSPSC
12352005
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dmt-dc-bz-phosphoramidite-13c9-15n3.html
Solubility
10 mM in DMSO
Smiles
CC(N(P(O[13C@H]1[13CH2][13C@@]([H])(O[13C@@H]1[13CH2]OC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)[15N]5[13C]([15N]=[13C]([15NH]C(C6=CC=CC=C6)=O)[13CH]=[13CH]5)=O)OCCC#N)C(C)C)C
Molecular Formula
C37 13C9H52N2 15N3O8P
Molecular Weight
845.82
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26 (41) :8857-8861.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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