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Moxonidine (Standard)

Moxonidine (Standard) is the analytical standard of Moxonidine. This product is intended for research and analytical applications. Moxonidine (BDF5895) is an orally active imidazoline type 1 receptor (I1-R) agonist. Moxonidine activates imidazoline I1 receptors and α2 adrenoceptors, affecting oxidized low-density lipoprotein uptake. Moxonidine reduces atherosclerotic lesions and lowers blood pressure. Moxonidine can be used in the study of hypertension, heart failure, and atherosclerosis[1][2][3][4][5][6][7].

Product Specifications

CAS Number

75438-57-2

Product Name Alternative

BDF5895 (Standard)

UNSPSC

12352005

Target

Adrenergic Receptor; Imidazoline Receptor; LDLR; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/moxonidine-standard.html

Smiles

CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1

Molecular Formula

C9H12ClN5O

Molecular Weight

241.68

References & Citations

[1]Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303 (3) : p. 1163-70.|[2]Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132 (4) : p. 991-1007.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

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