Metallo-β-lactamase-IN-13
Metallo-β-lactamase-IN-13 (Compound 13i) is a pan Metallo-β-Lactamase inhibitor. Metallo-β-lactamase-IN-13 provides broader coverage of metallo-β-lactamases expressing Gram-negative (GN) bacteria. Metallo-β-lactamase-IN-13 has antibacterial activity against P. aeruginosa[1].
Product Specifications
CAS Number
1802366-23-9
UNSPSC
12352005
Target
Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/metallo-β-lactamase-in-13.html
Solubility
10 mM in DMSO
Smiles
O=S(N)(C1=C(C2=NN=NN2)C(C3=C4N=C(N)SC4=CC=C3)=CC=C1C(F)(F)F)=O
Molecular Formula
C15H10F3N7O2S2
Molecular Weight
441.41
References & Citations
[1]Dong S, et al. Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration. J Med Chem. 2024 Feb 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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