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DAPK1 (Phospho-Ser308) rabbit pAb

Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Product Specifications

Background

Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

UniProt

P53355

Swiss Prot

P53355

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human DAPK1 (Phospho-Ser308)

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; WB

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, WB 1:500-2000

Molecular Weight

160kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

160kD

Fragment

IgG

Subcellular Location

[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton.

Other Product Names

Death-associated protein kinase 1 (DAP kinase 1; EC 2.7.11.1)

Gene ID (Human)

1612

Available Sizes

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