Thioredoxin reductase peptide

Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense[1][2].

Product Specifications

CAS Number

[950890-23-0]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/thioredoxin-reductase-peptide.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(N[C@H](C(O)=O)CCCCN)=O)[C@H]([C@@H](C)CC)NC([C@H](CS)NC(CNC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](CS)NC([C@H]([C@H](O)C)NC(CNC(CNC([C@H](CC(C)C)NC(CNC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C66H106N18O18S2

Molecular Weight

1503.79

References & Citations

[1]Jan YH, et al. Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis (2-chloroethyl) amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling. Chem Res Toxicol. 2014 Jan 21;27 (1) :61-75.|[2]Valette O, et al. Biochemical Function, Molecular Structure and Evolution of an Atypical Thioredoxin Reductase from Desulfovibrio vulgaris. Front Microbiol. 2017 Sep 29;8:1855.