YYA-021

YYA-021 is a small-molecule CD4 mimic that inhibits HIV entry, with high anti-HIV activity and low cytotoxicity[1][2].

Product Specifications

CAS Number

[144217-65-2]

UNSPSC

12352005

Hazard Statement

H302, H319, H372, H410

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/YYA-021.html

Purity

98.96

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(C)C=C1)C(NC2CC(C)(C)NC(C)(C)C2)=O

Molecular Formula

C18H27N3O2

Molecular Weight

317.43

Precautions

H302, H319, H372, H410

References & Citations

[1]Mizuguchi T, et al. A minimally cytotoxic CD4 mimic as an HIV entry inhibitor. Bioorg Med Chem Lett. 2016 Jan 15;26 (2) :397-400.|[2]Hashimoto C, et al. A CD4 mimic as an HIV entry inhibitor: pharmacokinetics. Bioorg Med Chem. 2013 Dec 15;21 (24) :7884-9.