3-Hydroxybenzoic acid

3-Hydroxybenzoic acid is an orally active endogenous metabolite. 3-Hydroxybenzoic acid is an agonist for GPR81 and GPR109A. 3-Hydroxybenzoic acid acts as stress response desensitizers. 3-Hydroxybenzoic acid can be used for anti-inflammatory and analgesic study[1][2][3].

Product Specifications

CAS Number

[99-06-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Hydroxycarboxylic Acid Receptor (HCAR)

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/3-Hydroxybenzoic_acid.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C1=CC(O)=CC=C1)=O

Molecular Formula

C7H6O3

Molecular Weight

138.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Liu C, et al. 3,5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J Pharmacol Exp Ther. 2012 Jun;341 (3) :794-801.|[2]Saba Anjum Khan et al. Potential Anti-Stress, Anxiolytic and Antidepressant Like Activities of Mono-Hydroxybenzoic Acids and Aspirin in Rodents: A Comparative Study. Austin J Pharmacol Ther. Volume 3 Issue 3-2015.|[3]Khan SA, Chatterjee SS, Kumar V. Low dose aspirin like analgesic and anti-inflammatory activities of mono-hydroxybenzoic acids in stressed rodents. Life Sci. 2016 Mar 1;148:53-62.