(S) -Alaproclate
(S) -Alaproclate ((S) -GEA 654) is more potent than the R- (+) -enantiomer both in blocking the NMDA receptor currents in vitro and in antagonizing the cGMP increase in vivo[1].
Product Specifications
CAS Number
66171-75-3
Product Name Alternative
(S) -GEA 654; (S) -A03
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-alaproclate.html
Smiles
C[C@H](N)C(OC(C)(C)CC1=CC=C(C=C1)Cl)=O
Molecular Formula
C13H18ClNO2
Molecular Weight
255.74
References & Citations
[1]P S Hu, et al. NMDA receptor-mediated increase in cyclic GMP in the rat cerebellum in vivo is blocked by alaproclate and GEA-857. Pharmacol Toxicol. 1997 Feb;80 (2) :97-102.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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