MitoB-d15 (bromide)
Product Specifications
UNSPSC Description
MitoB-d15 (bromide) is deuterium labeled MitoB (bromide). MitoB bromide is an exomarker of mitochondrial hydrogen peroxide. MitoB bromide is a mitochondria-targeted ratiometric probe, and can be used to measure levels of one major ROS, hydrogen peroxide, within living animals[1][2].
Target Antigen
Isotope-Labeled Compounds; Reactive Oxygen Species
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others
Field of Research
Inflammation/Immunology
Smiles
OB(C1=CC=CC(C[P+](C2=C(C([2H])=C(C([2H])=C2[2H])[2H])[2H])(C3=C(C([2H])=C(C([2H])=C3[2H])[2H])[2H])C4=C(C([2H])=C(C([2H])=C4[2H])[2H])[2H])=C1)O.[Br-]
Molecular Weight
492.23
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Salin K, et al. Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress. Sci Rep. 2017 Jan 24;7:41228.|[3]Cochemé HM, et al. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nat Protoc. 2012 Apr 19;7(5):946-58.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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