2F-Peracetyl-Fucose

2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor[1].

Product Specifications

CAS Number

[188783-78-0]

Product Name Alternative

1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Glycosyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2f-peracetyl-fucose.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)

Smiles

C[C@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](F)C(OC(C)=O)O1

Molecular Formula

C12H17FO7

Molecular Weight

292.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Martina Zimmermann, et al. Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation. Antibodies (Basel) . 2019 Jan 10;8 (1) :9.|[2]Desiderio V, et al. Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells. Oncotarget. 2015 Jan 1;6 (1) :71-84.|[3]Park S, et al. Altered expression of fucosylation pathway genes is associated with poor prognosis and tumor metastasis in non‑small cell lung cancer. Int J Oncol. 2020 Feb;56 (2) :559-567.