2F-Peracetyl-Fucose
2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor[1].
Product Specifications
CAS Number
188783-78-0
Product Name Alternative
1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Glycosyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2f-peracetyl-fucose.html
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic)
Smiles
C[C@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](F)C(OC(C)=O)O1
Molecular Formula
C12H17FO7
Molecular Weight
292.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Martina Zimmermann, et al. Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation. Antibodies (Basel) . 2019 Jan 10;8 (1) :9.|[2]Desiderio V, et al. Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells. Oncotarget. 2015 Jan 1;6 (1) :71-84.|[3]Park S, et al. Altered expression of fucosylation pathway genes is associated with poor prognosis and tumor metastasis in non‑small cell lung cancer. Int J Oncol. 2020 Feb;56 (2) :559-567.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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