Ethyl phenylglyoxylate

Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions[1][2][3].

Product Specifications

CAS Number

[1603-79-8]

Product Name Alternative

Ethyl benzoylformate; Phenylglyoxylic acid ethyl ester

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Carboxylesterase (CES) ; Drug Intermediate

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ethyl-phenylglyoxylate.html

Concentration

10mM

Purity

99.51

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCOC(C(C1=CC=CC=C1)=O)=O

Molecular Formula

C10H10O3

Molecular Weight

178.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Shengkui Hu, et al. Photochemically Active Polymers Containing Pendant Ethyl Phenylglyoxylate. Macromolecules 1998, 31, 2, 322–327.|[2]Hu S, et al. Photoreduction of ethyl phenylglyoxylate. Journal of Photochemistry and Photobiology A: Chemistry, 1998, 114 (2) : 103-108.|[3]Berndt M C, et al. Ethyl phenylglyoxylate, a simultaneous inhibitor and substrate of chicken liver carboxylesterase (EC 3.1. 1.1) . Enzyme-catalyzed fragmentation of (E) -benzil monoxime O-2, 4-dinitrophenyl ether. Journal of the American Chemical Society, 1977, 99 (25) : 8334-8335.