DIM-C-pPhOCH3
DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.
Product Specifications
CAS Number
[33985-68-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nuclear Hormone Receptor 4A/NR4A
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DIM-C-pPhOCH3.html
Purity
99.65
Solubility
DMSO : ≥ 33.3 mg/mL
Smiles
COC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1
Molecular Formula
C24H20N2O
Molecular Weight
352.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Cho SD, et al. Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways. Cancer Res. 2007 Jan 15;67 (2) :674-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nur77/NR4A1
Available Sizes
Curated Selection
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