EP2 receptor antagonist-1

EP2 receptor antagonist-1 (compound 1) is a potent, reversible, and agonist dependent allosteric prostaglandin EP2 receptor antagonist. EP2 receptor antagonist-1 shows anti-inflammatory effects[1].

Product Specifications

CAS Number

[848920-08-1]

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ep2-receptor-antagonist-1.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=C(N)N(C2=CC=C3OCCOC3=C2)C4=C1N=C5C=CC=CC5=N4)OCC6OCCC6

Molecular Formula

C24H22N4O5

Molecular Weight

446.46

References & Citations

[1]Jiang C, et, al. An Agonist Dependent Allosteric Antagonist of Prostaglandin EP2 Receptors. ACS Chem Neurosci. 2020 May 20;11 (10) :1436-1446.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Available Sizes

Curated Selection

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