Eniporide hydrochloride

Eniporide hydrochloride (EMD-96785 hydrochloride) is a potent Na+/H+ exchange inhibitor.

Product Specifications

CAS Number

[211813-86-4]

Product Name Alternative

EMD-96785 hydrochloride

UNSPSC

12352005

Target

Na+/H+ Exchanger (NHE)

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Eniporide_hydrochloride.html

Purity

99.49

Solubility

DMSO : 55 mg/mL (ultrasonic) |H2O : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CS(=O)(C1=C(N2C=CC=C2)C=C(C)C(C(NC(N)=N)=O)=C1)=O.[H]Cl

Molecular Formula

C14H17ClN4O3S

Molecular Weight

356.83

References & Citations

[1]Klass O, et al. Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. Ann Thorac Surg. 2004 Feb;77 (2) :658-63.|[2]Zeymer U, et al. The Na (+) /H (+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol. 2001 Nov 15;38 (6) :1644-50.