Dihydrocapsaicin-d3
Product Specifications
UNSPSC Description
Dihydrocapsaicin-d3 is the deuterium labeled Dihydrocapsaicin (HY-N0361)[1]. Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[2][3][4].
Target Antigen
Akt; Apoptosis; Bcl-2 Family; Caspase; Isotope-Labeled Compounds; PI3K; Reactive Oxygen Species; TRP Channel
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB;Others;PI3K/Akt/mTOR
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
CC(C)CCCCCCC(NCC1=CC=C(O)C(OC([2H])([2H])[2H])=C1)=O
Molecular Weight
310.45
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Shipping Conditions
Room temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Clinical Information
No Development Reported
CAS Number
1330261-21-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6367827-01 0.2 mL
ZNF813, NT (ZNF813, Zinc finger protein 813) (Azide free) (HRP)
Ask
View Details 
MBS6367827-02 5x 0.2 mL
ZNF813, NT (ZNF813, Zinc finger protein 813) (Azide free) (HRP)
Ask
View Details 