Iopanoic acid
Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium.
Product Specifications
CAS Number
[96-83-3]
UNSPSC
12352005
Hazard Statement
H302
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/Iopanoic_acid.html
Concentration
10mM
Purity
98.58
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)C(CC)CC1=C(I)C=C(I)C(N)=C1I
Molecular Formula
C11H12I3NO2
Molecular Weight
570.93
Precautions
H302
References & Citations
[1]Tuca A, et al. Inhibition of iodothyronine 5'-deiodinase by iopanoic acid does not block nuclear T3 accumulation during rat fetal development. Pediatr Res. 1994 Jan;35 (1) :91-5.|[2]Szabolcs I, et al. Effects of triiodothyronine, triiodothyroacetic acid, iopanoic acid and iodide on the thyrotropin-releasing hormone-induced thyrotropin release from superfused rat pituitary fragments. Acta Endocrinol (Copenh) . 1991 Oct;125 (4) :427-34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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