5-HT2C agonist-3
5-HT2C agonist-3 ((+) -19) is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM) . 5-HT2C agonist-3 has antipsychotic drug-like activity. 5-HT2C agonist-3 blocks Amphetamine-induced hyperactivity[1].
Product Specifications
CAS Number
2104810-18-4
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht2c-agonist-3.html
Concentration
10mM
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC(C=CC=C1)=C1CNC[C@@H]2[C@@H](C3=C(C=CC(F)=C3)OC)C2.[H]Cl
Molecular Formula
C19H23ClFNO2
Molecular Weight
351.84
References & Citations
[1]Guiping Zhang, et al. Discovery of N-Substituted (2-Phenylcyclopropyl) methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. J. Med. Chem. 2017, 60, 14, 6273–6288.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Available Sizes
Frequently Asked Questions
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