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DCK rabbit pAb

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]

UniProt

P27707

Swiss Prot

P27707

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human DCK AA range: 62-112

Target

DCK

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Nucleus .

Gene ID (Human)

1633

Available Sizes

Curated Selection

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