(-) -Camphoric acid

(-) -Camphoric acid is the less active enantiomer of Camphoric acid. Camphoric acid induces glutamate receptor expression. Camphoric acid also significantly induces the activation of NF-κB and AP-1. Camphoric acid significantly stimulates the differentiation of mouse osteoblastic MC3T3-E1 subclone 4 cells. Camphoric acid has weak regulatory function towards glutamate receptors. Camphoric acid can induce mRNA expression of glutamate signaling molecules and activate transcription factors, thereby stimulating osteoblast differentiation[1][2].

Product Specifications

CAS Number

[560-09-8]

UNSPSC

12352211

Hazard Statement

H302

Target

AP-1; mGluR; NF-κB

Type

Natural Products

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/minus-camphoric-acid.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C([C@]1(C)C(C)(C)[C@H](C(O)=O)CC1)O

Molecular Formula

C10H16O4

Molecular Weight

200.23

Precautions

H302

References & Citations

[1]Su-Ui Lee, et al. Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression. Amino Acids. 2010 Jan;38 (1) :85-93.|[2]Lee, S. U., et al., (2010) . Camphoric acid stimulates osteoblast differentiation and induces glutamate receptor expression. Amino acids, 38 (1), 85–93.