Thielavin B
Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously[1].
Product Specifications
CAS Number
71950-67-9
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/thielavin-b.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C(O)=C(C(C)=C1)C(OC2=C(C(C)=C(C(OC)=C2C)C(OC3=C(C(C)=C(C(OC)=C3C)C(O)=O)C)=O)C)=O)C
Molecular Formula
C31H34O10
Molecular Weight
566.60
References & Citations
[1]Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo) . 1981;34 (12) :1562-1568.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
EP
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