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Adipokinetic hormone (Gryllus bimaculatus)

Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) is an adipokinetic hormone that regulates energy homeostasis in insects by mobilizing lipid and carbohydrate from the fat body. Adipokinetic hormone Gryllus bimaculatus stimulates the locomotor activity of the two-spotted cricket. Adipokinetic hormone Gryllus bimaculatus can also be used in studies to regulate body weight, induce weight loss and alleviate glycogen storage disorders in humans[1][2][3].

Product Specifications

CAS Number

113800-65-0

Product Name Alternative

Grybi-AKH

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/adipokinetic-hormone-gryllus-bimaculatus.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1CCC(N1)=O)N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(NCC(N[C@H](C(N)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O

Molecular Formula

C43H57N11O12

Molecular Weight

919.98

References & Citations

[1]Lorenz M W, et al. Lipid mobilization and locomotor stimulation in Gryllus bimaculatus by topically applied adipokinetic hormone[J]. Physiological Entomology, 2004, 29 (2) : 146-151. |[2]Zhou YJ, et al. Effects of adipokinetic hormone and its related peptide on maintaining hemolymph carbohydrate and lipid levels in the two-spotted cricket, Gryllus bimaculatus. Biosci Biotechnol Biochem. 2018 Feb;82 (2) :274-284. |[3]Bernice Z. Schacter, et al. Compositions and methods for promoting lipid mobilization, glycogen mobilization, or both, in humans. Patent WO2003066080A1.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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