(±) 16-HDHA

(±) 16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±) 16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

Product Specifications

CAS Number

[90780-51-1]

Product Name Alternative

(±) 16-HDoHE; 16-hydroxy Docosahexaenoic acid; (±) 16-HDoHE

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/racemic-16-hdha.html

Smiles

CC/C=C\C=C\C(O)C/C=C\C/C=C\C/C=C\C/C=C\CCC(O)=O

Molecular Formula

C22H32O3

Molecular Weight

344.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]VanRollins, et al. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25 (5), 507-517 (1984) .