2,5-Di-tert-butyl-1,4-benzoquinone

2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent that defends the emerging antibacterial resistance, which is found in marine Streptomyces sp. VITVSK1. 2,5-Di-tert-butyl-1,4-benzoquinone is also a potent inhibitor of RNA polymerase[1][2].

Product Specifications

CAS Number

[2460-77-7]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Bacterial; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-5-di-tert-butyl-1-4-benzoquinone.html

Purity

99.78

Smiles

O=C1C=C(C(C)(C)C)C(C=C1C(C)(C)C)=O

Molecular Formula

C14H20O2

Molecular Weight

220.31

Precautions

H315, H319, H335

References & Citations

[1]2,5-di-tert-butyl-1,4-benzoquinone (DTBBQ) from Streptomyces sp. VITVSK1 as a potent antibacterial agent. Int J Bioinform Res Appl. 2015;11 (2) :142-52. |[2]Crawford H M, et al. The Reactions of Phenanthrenequinone and 2, 5-Di-t-butyl-1, 4-benzoquinone with Phenyllithium and with Phenylmagnesium Bromide1, 2[J]. Journal of the American Chemical Society, 1952, 74 (16) : 4087-4088.