Depatuxizumab

Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. Depatuxizumab can be used for research on cancer[1].

Product Specifications

CAS Number

[1471999-69-5]

Product Name Alternative

ABT-806

UNSPSC

12352203

Target

EGFR

Type

Inhibitory Antibodies

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/depatuxizumab.html

Purity

99.58

Solubility

10 mM in DMSO

Smiles

[Depatuxizumab]

Molecular Weight

(144.54 kDa)

References & Citations

[1]Reilly EB, et al. Characterization of ABT-806, a Humanized Tumor-Specific Anti-EGFR Monoclonal Antibody. Mol Cancer Ther. 2015 May;14 (5) :1141-51.