Menaquinone-4-d7
Menaquinone-4-d7 (Vitamin K2 (MK-4) -d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
Product Specifications
CAS Number
1233937-25-1
Product Name Alternative
Vitamin K2 (MK-4) -d7; Menaquinone K4-d7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
97.84
Solubility
10 mM in DMSO
Smiles
O=C1C=2C(C(=O)C(C([2H])([2H])[2H])=C1C/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)=C(C(=C(C2[2H])[2H])[2H])[2H]
Molecular Formula
C31H33D7O2
Molecular Weight
451.69
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Noda S, et al. Menaquinone-4 (vitamin K2) up-regulates expression of human intestinal alkaline phosphatase in Caco-2 cells. Nutr Res. 2016 Nov;36 (11) :1269-1276.|[3]Kim M, et al. Vitamin K1 (phylloquinone) and K2 (menaquinone-4) supplementation improves bone formation in a high-fat diet-induced obese mice. J Clin Biochem Nutr. 2013 Sep;53 (2) :108-13.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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